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CS-W001157 4
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2-{2-[(tert-Butoxy)carbonyl]-2-azaspiro[3.3]heptan-6-yl}acetic acid

  • CAS No. 1251002-39-7

  • Cat. No. CS-0052078
  • Purity≥97%
  • MDL No.MFCD17016195

*For research and further manufacturing use only, not for direct human use.

2-{2-[(tert-Butoxy)carbonyl]-2-azaspiro[3.3]heptan-6-yl}acetic acid|CS-0052078

Structure of 1251002-39-7

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General Information

  • CAS No. 1251002-39-7
  • Cat. No. CS-0052078
  • Purity ≥97%
  • MDL No. MFCD17016195
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₁NO₄
  • Molecular Weight 255.31
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)N1CC2(C1)CC(CC(=O)O)C2

Description

This spirocyclic amino acid derivative features a protected 2-azaspiro[3.3]heptane core with a tert-butoxycarbonyl group, enabling stable incorporation into peptide sequences. The pendant acetic acid moiety provides a handle for conjugation or derivatization under standard conditions.

Application

2-{2-[(tert-Butoxy)carbonyl]-2-azaspiro[3.3]heptan-6-yl}acetic acid serves as a versatile spirocyclic building block for medicinal chemistry and peptide-based scaffold synthesis. The protected azaspiro core exhibits excellent bench stability and facilitates orthogonal functionalization, enabling efficient access to complex heterocycles. Its carboxylic acid functionality supports direct coupling reactions or derivatization, while the tert-butoxycarbonyl group provides robust protection under standard synthetic conditions.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   66.84
  • LogP   2.1082
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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