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CS-W001157 4
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Edoxaban impurity 11

  • CAS No. 365998-36-3

  • Cat. No. CS-0054366
  • Purity≥98%
  • MDL No.MFCD22190570

*For research and further manufacturing use only, not for direct human use.

Edoxaban impurity 11|CS-0054366

Structure of 365998-36-3

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General Information

  • CAS No. 365998-36-3
  • Cat. No. CS-0054366
  • Purity ≥98%
  • MDL No. MFCD22190570
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₇N₃O₃
  • Molecular Weight 285.38
  • Synonym(s) None
  • SMILES O=C(N[C@H]1[C@H](CC[C@@H](C1)C(N(C)C)=O)N)OC(C)(C)C

Description

tert-Butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate is a stereochemically defined cyclohexyl carbamate featuring a protected primary amine and a dimethylcarbamoyl group. This configuration enables selective incorporation into peptidomimetic scaffolds and bioactive molecule synthesis under standard bench conditions.

Application

tert-Butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate serves as a versatile chiral building block for the synthesis of bioactive cyclohexane-containing scaffolds. Its protected amine and carbamate functionalities enable orthogonal manipulation in multi-step sequences, while the dimethylcarbamoyl group enhances solubility and stability. The compound exhibits robust bench stability and facilitates efficient purification, making it well-suited for medicinal chemistry campaigns and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   84.66
  • LogP   1.0953
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

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