4-(3,4-Difluorophenyl)thiazol-2-amine

Name: 4-(3,4-Difluorophenyl)thiazol-2-amine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 175135-32-7
Cat. No. CS-0157111
Purity≥98%
MDL No.MFCD00052876

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-(3,4-Difluorophenyl)thiazol-2-amine|CS-0157111

Structure of 175135-32-7

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 175135-32-7
Cat. No. CS-0157111
Purity ≥98%
MDL No. MFCD00052876
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₆F₂N₂S
Molecular Weight 212.22
Synonym(s) 4-(3,4-Difluorophenyl)-1,3-thiazol-2-amine
SMILES NC1=NC(C2=CC=C(F)C(F)=C2)=CS1

Description

4-(3,4-Difluorophenyl)thiazol-2-amine features a fluorinated aryl moiety that enhances metabolic stability and membrane permeability. The thiazole scaffold provides a rigid, electron-deficient platform ideal for hydrogen bonding and π–stacking interactions in target binding. This compound serves as a key building block in kinase inhibitor and medicinal chemistry libraries, offering improved solubility and synthetic versatility under standard conditions.

Application

4-(3,4-Difluorophenyl)thiazol-2-amine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through palladium-catalyzed cross-coupling and electrophilic substitution reactions. The thiazole core exhibits robust bench stability and tolerates a range of functional groups, facilitating efficient synthesis of pharmaceutical intermediates and kinase inhibitor scaffolds. Its dual aromatic systems support π–π interactions in target binding, enhancing molecular recognition potential.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H319
Precautionary Statements : P264-P270-P280-P330-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 38.91
LogP 2.6705
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Fluoride

Building Blocks Skeleton Aromatic heterocycle compounds Thiazole compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

4-(3,4-Difluorophenyl)thiazol-2-amine sigma4-(3,4-Difluorophenyl)thiazol-2-amine manufacturer4-(3,4-Difluorophenyl)thiazol-2-amine price4-(3,4-Difluorophenyl)thiazol-2-amine structure4-(3,4-Difluorophenyl)thiazol-2-amine SDSbuy 4-(3,4-Difluorophenyl)thiazol-2-amine4-(3,4-Difluorophenyl)thiazol-2-amine supplier4-(3,4-Difluorophenyl)thiazol-2-amine uses4-(3,4-Difluorophenyl)thiazol-2-amine molecular weightprice of 4-(3,4-Difluorophenyl)thiazol-2-amine4-(3,4-Difluorophenyl)thiazol-2-amine chemical name formula of 4-(3,4-Difluorophenyl)thiazol-2-amine

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

4-(3,4-Difluorophenyl)thiazol-2-amine

CAS No. 175135-32-7

Recommended Products