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CS-W001157 4
Total: USD 88.00

Azido-PEG2-C2-amine

  • CAS No. 166388-57-4

  • Cat. No. CS-0114352
  • Purity≥97%
  • MDL No.MFCD13189985

*For research and further manufacturing use only, not for direct human use.

Azido-PEG2-C2-amine|CS-0114352

Structure of 166388-57-4

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General Information

  • CAS No. 166388-57-4
  • Cat. No. CS-0114352
  • Purity ≥97%
  • MDL No. MFCD13189985
  • Storage -20°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₄N₄O₂
  • Molecular Weight 174.20
  • Synonym(s) N3-PEG2-CH2CH2NH2
  • SMILES [N-]=[N+]=NCCOCCOCCN

Description

Azido-PEG2-C2-amine features a reactive azide group linked via a short PEG2 spacer to a terminal amine, enabling efficient bioconjugation through strain-promoted or copper-catalyzed azide-alkyne cycloaddition. This bifunctional handle combines excellent solubility with reliable reactivity, facilitating site-specific labeling and conjugation in aqueous environments.

Synthesis

  • Route1

    References

    • Klein, Emmanuel; DeBonis, Salvatore; Thiede, Bernd; Skoufias, Dimitrios A.; Kozielski, Frank; Lebeau, Luc Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 19 p. 6474 - 6488
  • Route2

    References

    • Li, Ying; Schaffer, Paul; Perrin, David M. Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 23 p. 6313 - 6316
  • Route3

    References

    • Lu, Yan; Gervay-Hague, Jacquelyn Carbohydrate Research, 2007 , vol. 342, # 12-13 p. 1636 - 1650

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3265
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

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Computational Chemistry Data

  • TPSA   93.24
  • LogP   0.2886
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   8

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