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CS-W001157 4
Total: USD 88.00

Bis-NH2-PEG2

  • CAS No. 929-59-9

  • Cat. No. CS-0100622
  • Purity≥96%
  • MDL No.MFCD00040474

*For research and further manufacturing use only, not for direct human use.

Bis-NH2-PEG2|CS-0100622

Structure of 929-59-9

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General Information

  • CAS No. 929-59-9
  • Cat. No. CS-0100622
  • Purity ≥96%
  • MDL No. MFCD00040474
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₆N₂O₂
  • Molecular Weight None
  • Synonym(s) PROTAC Linker 19
  • SMILES NCCOCCOCCN

Description

2,2-(ethylenedioxy)-bis-(ethylamine) (EDEA) was used to linker to form conjugates of:manganese-doped zinc sulfide nanoparticles with folic acid and dimeric neomycin-neomycin. Glycidyl groups of the l-GMA particles were reacted with EDEA to produce large amine-functionalized particles (l-NH2). Polycondensation of guanidine hydrochloride and 2,2-(ethylenedioxy)bis(ethylamine) has been used to measure biocides released into the environmental water samples.

Application

Bis-NH₂-PEG2 serves as a versatile bifunctional linker for conjugation and polymer synthesis, enabling efficient coupling of biomolecules, drugs, or functional groups via amine-reactive reagents. Its two terminal primary amines offer high reactivity with NHS esters, aldehydes, or activated carboxylates, while the PEG2 spacer provides enhanced solubility and reduced aggregation. The compound exhibits excellent bench stability and ease of purification, making it ideal for use in diagnostic labeling, drug delivery systems, and the construction of bioactive scaffolds.

Synthesis

  • Route1

    References

    • Journal of Heterocyclic Chemistry, , vol. 18, p. 297 - 302
  • Route2
    • null|null
      31255-11-5
    • ~87%
    • In-stock
      Bis-NH2-PEG2|CS-0100622
      929-59-9

    References

    • Journal of Organic Chemistry, , vol. 46, # 15 p. 3064 - 3070
  • Route3

    References

    • Journal of Organic Chemistry, , vol. 39, p. 1315 - 1316

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07,GHS08
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅱ
Hazard Statements : H302-H314-H317-H334
Precautionary Statements : P260-P261-P264-P270-P272-P280-P284-P301+P330+P331-P302+P352-P304+P340-P330-P362+P364-P363-P405-P501

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Computational Chemistry Data

  • TPSA   70.5
  • LogP   -1.063
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   7

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