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CS-W001157 4
Total: USD 88.00

Cbz-PEG2-C2-NH2

  • CAS No. 169744-02-9

  • Cat. No. CS-0447820
  • Purity≥97%
  • MDL No.MFCD28400772

*For research and further manufacturing use only, not for direct human use.

Cbz-PEG2-C2-NH2|CS-0447820

Structure of 169744-02-9

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General Information

  • CAS No. 169744-02-9
  • Cat. No. CS-0447820
  • Purity ≥97%
  • MDL No. MFCD28400772
  • Storage 4°C, sealed storage, away from moisture and light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₂N₂O₄
  • Molecular Weight 282.34
  • Synonym(s) None
  • SMILES O=C(OCC=1C=CC=CC1)NCCOCCOCCN

Description

Benzyl (2-(2-(2-aminoethoxy)ethoxy)ethyl)carbamate is a water-soluble, bench-stable protecting group reagent designed for selective amine derivatization. This carbamate moiety enables efficient conjugation of primary amines under mild conditions, offering high functional group tolerance and clean deprotection via acidolysis. The extended ethylene glycol spacer enhances solubility and reduces steric interference during coupling reactions.

Application

Benzyl (2-(2-(2-aminoethoxy)ethoxy)ethyl)carbamate serves as a robust, bench-stable amino-protecting group for amine-directed synthesis. It facilitates efficient conjugation and cleavage under mild acidic conditions, enabling selective functionalization in complex molecule assembly. The triethylene glycol-based spacer enhances solubility and compatibility with diverse reaction environments, making it ideal for peptide modification, combinatorial chemistry, and the construction of bioactive heterocyclic scaffolds.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   82.81
  • LogP   0.9047
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   10

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