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CS-W001157 4
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(R)-2-(1-(tert-Butoxycarbonyl)pyrrolidin-3-yl)acetic acid

  • CAS No. 204688-60-8

  • Cat. No. CS-0052119
  • Purity≥97%
  • MDL No.MFCD05861547

*For research and further manufacturing use only, not for direct human use.

(R)-2-(1-(tert-Butoxycarbonyl)pyrrolidin-3-yl)acetic acid|CS-0052119

Structure of 204688-60-8

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General Information

  • CAS No. 204688-60-8
  • Cat. No. CS-0052119
  • Purity ≥97%
  • MDL No. MFCD05861547
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₉NO₄
  • Molecular Weight 229.28
  • Synonym(s) [(3R)-1-(tert-butoxycarbonyl)pyrrolidin-3-yl]acetic acid
  • SMILES CC(C)(C)OC(=O)N1CC[C@H](CC(O)=O)C1

Description

(R)-2-(1-(tert-Butoxycarbonyl)pyrrolidin-3-yl)acetic acid features a chiral pyrrolidine core with a protected amine and a carboxylic acid handle, enabling direct incorporation into peptide synthesis. This bench-stable derivative facilitates efficient access to bioactive analogs through orthogonal deprotection strategies.

Application

(R)-2-(1-(tert-Butoxycarbonyl)pyrrolidin-3-yl)acetic acid serves as a versatile chiral building block for the synthesis of pyrrolidine-containing peptidomimetics and bioactive heterocycles. The Boc-protected amine enables orthogonal functionalization, while the pendant acetic acid facilitates conjugation or further derivatization. Its bench-stable, crystalline nature supports straightforward handling and purification, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development.

Safety Information

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GHS Pictogram :
GHS No : GHS06,GHS09
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H410
Precautionary Statements : P264-P270-P330-P405-P501

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Computational Chemistry Data

  • TPSA   66.84
  • LogP   1.7181
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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