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Thiazol-2-ylmethanamine hydrochloride

  • CAS No. 850852-85-6

  • Cat. No. CS-0054610
  • Molecule weight150.63
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Thiazol-2-ylmethanamine hydrochloride|CS-0054610

Structure of 850852-85-6

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General Information

  • CAS No. 850852-85-6
  • Cat. No. CS-0054610
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₇ClN₂S
  • Molecular Weight 150.63
  • Synonym(s) 2-thiazolylmethanamine hydrochloride
  • SMILES NCC1=NC=CS1.Cl

Description

Thiazol-2-ylmethanamine hydrochloride offers a bench-stable, moisture-tolerant scaffold for constructing bioactive molecules. The thiazole ring provides electron-deficient character ideal for hydrogen bonding and π-stacking interactions. This amine functionality enables direct coupling in peptide-like syntheses or as a building block in medicinal chemistry campaigns targeting kinase inhibitors and antimicrobial agents.

Application

Thiazol-2-ylmethanamine hydrochloride serves as a versatile building block for thiazole-based scaffolds, enabling efficient access to bioactive heterocycles. Its amine functionality facilitates straightforward derivatization via amidation, alkylation, and reductive amination, while the protonated form ensures excellent solubility and stability in polar solvents. This compound functions as a key intermediate in medicinal chemistry campaigns targeting kinase inhibitors and antimicrobial agents, offering high compatibility with standard synthetic workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   1.0236
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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