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CS-W001157 4
Total: USD 88.00

3-Bromo-1H-pyrrolo[3,2-c]pyridine

  • CAS No. 23612-36-4

  • Cat. No. CS-W006499
  • Purity≥97%
  • MDL No.MFCD08690126

*For research and further manufacturing use only, not for direct human use.

3-Bromo-1H-pyrrolo[3,2-c]pyridine|CS-W006499

Structure of 23612-36-4

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General Information

  • CAS No. 23612-36-4
  • Cat. No. CS-W006499
  • Purity ≥97%
  • MDL No. MFCD08690126
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅BrN₂
  • Molecular Weight 197.03
  • Synonym(s) 3-BROMO-5-AZAINDOLE
  • SMILES BrC1=CNC2=C1C=NC=C2

Description

3-Bromo-1H-pyrrolo[3,2-c]pyridine is a heteroaromatic building block featuring a brominated pyrrolopyridine core. This electron-deficient scaffold enables direct functionalization in cross-coupling reactions, integrating seamlessly into pharmaceutical and agrochemical scaffolds. The molecule exhibits robust stability under standard reaction conditions and facilitates efficient derivatization via palladium-catalyzed transformations.

Application

3-Bromo-1H-pyrrolo[3,2-c]pyridine serves as a versatile heterocyclic building block for medicinal chemistry and catalytic cross-coupling reactions. The bromine substituent enables reliable Suzuki, Stille, and Negishi couplings, facilitating the construction of biaryl and complex polycyclic scaffolds. Its stability under standard reaction conditions and compatibility with diverse functional groups make it a practical choice for synthesizing kinase inhibitors and other bioactive compounds.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   28.68
  • LogP   2.3254
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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