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tert-Butyl 3-bromo-1H-pyrrolo[3,2-c]pyridine-1-carboxylate

  • CAS No. 192189-16-5

  • Cat. No. CS-0041109
  • Molecule weight297.15
  • Purity≥97%
  • MDL No.MFCD16877631

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 3-bromo-1H-pyrrolo[3,2-c]pyridine-1-carboxylate|CS-0041109

Structure of 192189-16-5

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General Information

  • CAS No. 192189-16-5
  • Cat. No. CS-0041109
  • Purity ≥97%
  • MDL No. MFCD16877631
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₃BrN₂O₂
  • Molecular Weight 297.15
  • Synonym(s) tert-butyl 3-bromopyrrolo[3,2-c]pyridine-1-carboxylate
  • SMILES O=C(N1C=C(Br)C2=C1C=CN=C2)OC(C)(C)C

Description

tert-Butyl 3-bromo-1H-pyrrolo[3,2-c]pyridine-1-carboxylate features a brominated pyrrolopyridine core with a bench-stable tert-butyl ester handle. This electrophilic scaffold enables direct coupling in cross-coupling reactions and integrates readily into complex heterocyclic architectures under standard conditions.

Application

tert-Butyl 3-bromo-1H-pyrrolo[3,2-c]pyridine-1-carboxylate serves as a versatile building block for the synthesis of substituted pyrrolopyridine scaffolds. The bromo group enables palladium-catalyzed cross-coupling reactions, while the tert-butyl ester provides stability and convenient deprotection under acidic conditions. Its compatibility with diverse functional groups and robust bench stability facilitate efficient access to complex heterocyclic architectures relevant in medicinal chemistry and materials science.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   44.12
  • LogP   3.582
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   0

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