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Structure of 175358-01-7
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3-Amino-6-chloropyridine-2-carboxamide features a pyridine core bearing amino, chloro, and carboxamide functionalities, enabling versatile integration into bioactive scaffolds. The electron-deficient ring facilitates nucleophilic substitution, while the amide group enhances solubility and hydrogen bonding capacity. This compound serves as a key intermediate in medicinal chemistry campaigns targeting kinase inhibitors and antimicrobial agents.
3-Amino-6-chloropyridine-2-carboxamide serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through nucleophilic substitution and coupling reactions. Its ortho-amino and carboxamide functionalities offer complementary reactivity for derivatization, while the chloro group facilitates transition-metal-catalyzed transformations. The compound exhibits bench stability and is compatible with standard purification protocols, making it well-suited for iterative synthesis campaigns in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: