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CS-W001157 4
Total: USD 88.00

3-Bromo-6-chloro-1H-pyrrolo[3,2-c]pyridine

  • CAS No. 1000341-61-6

  • Cat. No. CS-0051457
  • Purity≥97%
  • MDL No.MFCD09749982

*For research and further manufacturing use only, not for direct human use.

3-Bromo-6-chloro-1H-pyrrolo[3,2-c]pyridine|CS-0051457

Structure of 1000341-61-6

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General Information

  • CAS No. 1000341-61-6
  • Cat. No. CS-0051457
  • Purity ≥97%
  • MDL No. MFCD09749982
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄BrClN₂
  • Molecular Weight 231.48
  • Synonym(s) 1H-PYRROLO[3,2-C]PYRIDINE,3-BROMO-6-CHLORO
  • SMILES ClC1=NC=C2C(Br)=CNC2=C1

Description

3-Bromo-6-chloro-1H-pyrrolo[3,2-c]pyridine is a heterocyclic building block featuring bromo and chloro substituents at electron-rich positions, enabling direct functionalization in cross-coupling reactions. The fused pyrrole-pyridine core offers enhanced stability and defined electronic properties, facilitating integration into pharmaceutical intermediates and advanced materials.

Application

3-Bromo-6-chloro-1H-pyrrolo[3,2-c]pyridine serves as a versatile heterocyclic building block for the synthesis of pharmaceutical intermediates and agrochemical scaffolds. Its orthogonal halogenation pattern enables sequential cross-coupling reactions with high regiocontrol, facilitating efficient construction of complex biaryl and triaryl systems. The compound exhibits excellent bench stability and compatibility with standard Pd-catalyzed coupling conditions, simplifying purification and scale-up in medicinal chemistry workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H317
Precautionary Statements : P261-P264-P270-P272-P280-P302+P352-P330-P362+P364-P501

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Computational Chemistry Data

  • TPSA   28.68
  • LogP   2.9788
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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