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CS-W001157 4
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7-Bromo-4-chloro-1H-pyrrolo[3,2-c]pyridine

  • CAS No. 1000342-04-0

  • Cat. No. CS-0050079
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

7-Bromo-4-chloro-1H-pyrrolo[3,2-c]pyridine|CS-0050079

Structure of 1000342-04-0

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General Information

  • CAS No. 1000342-04-0
  • Cat. No. CS-0050079
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄BrClN₂
  • Molecular Weight 231.48
  • Synonym(s) 7-Bromo-4-chloro-5-azaindole
  • SMILES ClC1=NC=C(Br)C2=C1C=CN2

Description

7-Bromo-4-chloro-1H-pyrrolo[3,2-c]pyridine is a heterocyclic building block featuring complementary halogen substituents at electron-rich positions. This scaffold enables direct coupling in cross-coupling reactions and integrates readily into complex molecular architectures. The molecule exhibits robust stability under standard reaction conditions and facilitates efficient functionalization in medicinal chemistry and materials synthesis.

Application

7-Bromo-4-chloro-1H-pyrrolo[3,2-c]pyridine serves as a versatile heterocyclic building block for medicinal chemistry and materials science. Its dual halogenation enables efficient Pd-catalyzed cross-coupling reactions, facilitating the construction of complex biaryl and heteroaryl architectures. The molecule exhibits excellent bench stability and compatibility with diverse functional groups, simplifying purification and downstream derivatization in standard synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   28.68
  • LogP   2.9788
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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