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CS-W001157 4
Total: USD 88.00

4-Bromo-2-methyl-2H-pyrazolo[3,4-c]pyridine

  • CAS No. 2177257-61-1

  • Cat. No. CS-0045109
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Bromo-2-methyl-2H-pyrazolo[3,4-c]pyridine|CS-0045109

Structure of 2177257-61-1

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General Information

  • CAS No. 2177257-61-1
  • Cat. No. CS-0045109
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆BrN₃
  • Molecular Weight 212.05
  • Synonym(s) None
  • SMILES CN1N=C2C=NC=C(Br)C2=C1

Description

4-Bromo-2-methyl-2H-pyrazolo[3,4-c]pyridine is a heterocyclic scaffold featuring a bromine atom at the 4-position and a methyl group at the 2-position, enabling selective functionalization in medicinal chemistry. This electron-deficient core integrates readily into bioactive molecules, offering enhanced metabolic stability and tunable electronic properties for target-directed design.

Application

4-Bromo-2-methyl-2H-pyrazolo[3,4-c]pyridine serves as a versatile heterocyclic building block for medicinal chemistry and catalytic cross-coupling applications. The bromo group enables reliable Suzuki-Miyaura and Stille coupling reactions, while the methyl substituent enhances solubility and modulates electronic properties. This scaffold exhibits bench stability and compatibility with diverse reaction conditions, facilitating efficient construction of complex polycyclic architectures in API development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

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Computational Chemistry Data

  • TPSA   30.71
  • LogP   1.7308
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

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