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CS-W001157 4
Total: USD 88.00

4-Bromo-2-methyl-1,3-thiazole

  • CAS No. 298694-30-1

  • Cat. No. CS-0044498
  • Purity≥95%
  • MDL No.MFCD06409945

*For research and further manufacturing use only, not for direct human use.

4-Bromo-2-methyl-1,3-thiazole|CS-0044498

Structure of 298694-30-1

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General Information

  • CAS No. 298694-30-1
  • Cat. No. CS-0044498
  • Purity ≥95%
  • MDL No. MFCD06409945
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₄BrNS
  • Molecular Weight 178.05
  • Synonym(s) 4-Bromo-2-methylthiazole
  • SMILES CC1=NC(Br)=CS1

Description

4-Bromo-2-methyl-1,3-thiazole is a heterocyclic building block featuring a brominated thiazole core with a methyl group at the 2-position. This configuration imparts enhanced reactivity in cross-coupling processes, enabling efficient integration into pharmaceutical and agrochemical scaffolds under standard conditions.

Application

4-Bromo-2-methyl-1,3-thiazole serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its stable bromine substituent. The methyl group at the 2-position enhances regioselectivity in electrophilic functionalization, while the thiazole core provides excellent stability and compatibility with common protecting groups. Its bench-stable nature and predictable reactivity make it ideal for constructing complex scaffolds in medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   2.21402
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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