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CS-W001157 4
Total: USD 88.00

7-Bromo-1H-pyrazolo[4,3-c]pyridine

  • CAS No. 1256821-58-5

  • Cat. No. CS-0050099
  • Purity≥95%
  • MDL No.MFCD18256789

*For research and further manufacturing use only, not for direct human use.

7-Bromo-1H-pyrazolo[4,3-c]pyridine|CS-0050099

Structure of 1256821-58-5

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General Information

  • CAS No. 1256821-58-5
  • Cat. No. CS-0050099
  • Purity ≥95%
  • MDL No. MFCD18256789
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₄BrN₃
  • Molecular Weight 198.02
  • Synonym(s) None
  • SMILES BrC1=C2NN=CC2=CN=C1

Description

7-Bromo-1H-pyrazolo[4,3-c]pyridine is a heterocyclic scaffold featuring a brominated pyrazolopyridine core, offering a reactive handle for cross-coupling transformations. This bench-stable compound integrates readily into medicinal chemistry campaigns, enabling efficient access to bioactive molecules through palladium-catalyzed functionalization.

Application

7-Bromo-1H-pyrazolo[4,3-c]pyridine serves as a versatile building block for the synthesis of bioactive heterocycles, enabling efficient palladium-catalyzed cross-coupling reactions. Its bromine substituent provides high reactivity in Suzuki, Stille, and Negishi transformations, facilitating rapid diversification of pyrazolopyridine scaffolds. The compound exhibits excellent bench stability and is compatible with common protecting groups, making it well-suited for medicinal chemistry campaigns and API intermediate development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301
Precautionary Statements : P264-P270-P330-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   41.57
  • LogP   1.7204
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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