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CS-W001157 4
Total: USD 88.00

Fmoc-Pra-OH

  • CAS No. 198561-07-8

  • Cat. No. CS-W011926
  • Purity≥97%
  • MDL No.MFCD01075095

*For research and further manufacturing use only, not for direct human use.

Fmoc-Pra-OH|CS-W011926

Structure of 198561-07-8

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General Information

  • CAS No. 198561-07-8
  • Cat. No. CS-W011926
  • Purity ≥97%
  • MDL No. MFCD01075095
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₀H₁₇NO₄
  • Molecular Weight None
  • Synonym(s) None
  • SMILES C#CC[C@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)C(O)=O

Description

Fmoc-Pra-OH is a key building block for solid-phase peptide synthesis, featuring a benzyl-protected arginine side chain and a terminal carboxylic acid. This derivative enables efficient incorporation of arginine residues with minimal side reactions, offering high stability under standard coupling conditions and compatibility with automated synthesis platforms.

Synthesis

  • Route1
    • In-stock
      L-Propargylglycine|CS-W006064
      23235-01-0
    • null|null
      102774-86-7
    • ~66%
    • In-stock
      Fmoc-Pra-OH|CS-W011926
      198561-07-8

    References

    • Byrne, Cillian; McEwan, Paul A.; Emsley, Jonas; Fischer, Peter M.; Chan, Weng C. Chemical Communications, 2011 , vol. 47, # 9 p. 2589 - 2591
  • Route2
    • tert-Butyl (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)pent-4-ynoate|CS-1244174
      857335-00-3
    • ~96%
    • In-stock
      Fmoc-Pra-OH|CS-W011926
      198561-07-8

    References

    • Itoh, Hiroaki; Matsuoka, Shigeru; Kreir, Mohamed; Inoue, Masayuki Journal of the American Chemical Society, 2012 , vol. 134, # 34 p. 14011 - 14018
  • Route3

    References

    • Sminia, Tjerk Jacco; Pedersen, Daniel Sejer Synlett, 2012 , vol. 23, # 18 p. 2643 - 2646,4 Title/Abstract Full Text Show Details Sminia, Tjerk Jacco; Pedersen, Daniel Sejer Synlett, 2012 , vol. 23, # 18 p. 2643 - 2646

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   3.0016
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   5

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