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CS-W001157 4
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(S)-2-Aminopent-4-ynoic acid hydrochloride

  • CAS No. 198774-27-5

  • Cat. No. CS-0101207
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S)-2-Aminopent-4-ynoic acid hydrochloride|CS-0101207

Structure of 198774-27-5

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General Information

  • CAS No. 198774-27-5
  • Cat. No. CS-0101207
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₈ClNO₂
  • Molecular Weight 149.58
  • Synonym(s) L-Propargylglycine L-Propargylglycine
  • SMILES C#CC[C@@H](C(O)=O)N.[H]Cl

Description

(S)-2-Aminopent-4-ynoic acid hydrochloride features a chiral α-amino acid scaffold with a terminal alkyne group, enabling bioorthogonal conjugation. The hydrochloride salt enhances solubility and stability in aqueous media, facilitating use in peptide synthesis and chemical biology applications requiring site-specific labeling.

Application

(S)-2-Aminopent-4-ynoic acid hydrochloride serves as a versatile chiral building block for the synthesis of bioactive peptides and heterocyclic scaffolds. Its terminal alkyne and amino-carboxylic acid functionalities enable efficient CuAAC click chemistry, amide coupling, and cyclization reactions. The hydrochloride salt enhances bench stability and solubility, facilitating purification and handling in standard organic workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   63.32
  • LogP   -0.1566
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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