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CS-W001157 4
Total: USD 88.00

Fmoc-D-Pra-OH

  • CAS No. 220497-98-3

  • Cat. No. CS-W008395
  • Purity≥97%
  • MDL No.MFCD01311781

*For research and further manufacturing use only, not for direct human use.

Fmoc-D-Pra-OH|CS-W008395

Structure of 220497-98-3

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General Information

  • CAS No. 220497-98-3
  • Cat. No. CS-W008395
  • Purity ≥97%
  • MDL No. MFCD01311781
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₀H₁₇NO₄
  • Molecular Weight None
  • Synonym(s) None
  • SMILES C#CC[C@H](C(O)=O)NC(OCC1C2=C(C=CC=C2)C3=C1C=CC=C3)=O

Description

Fmoc-D-Pra-OH is a bench-stable, moisture-tolerant amino acid derivative featuring a fluorenylmethyloxycarbonyl-protected D-proline scaffold. This configuration enables efficient incorporation into peptide chains via standard solid-phase synthesis protocols, delivering enhanced solubility and reduced aggregation during elongation.

Application

Fmoc-D-Pra-OH serves as a key building block in peptide synthesis, enabling the incorporation of D-proline analogs with enhanced conformational rigidity. The Fmoc group facilitates orthogonal protection and efficient coupling under standard conditions, while the carboxylic acid functionality supports direct amide bond formation. Its bench-stable nature and compatibility with diverse coupling reagents make it ideal for synthesizing bioactive peptides and cyclic scaffolds.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   3.0016
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   5

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