Fmoc-Phe-OH

Name: Fmoc-Phe-OH
Brand: ChemScene
Availability: InStock
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CAS No. 35661-40-6
Cat. No. CS-W020026
Purity≥97%
MDL No.MFCD00037128

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 35661-40-6

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General Information

CAS No. 35661-40-6
Cat. No. CS-W020026
Purity ≥97%
MDL No. MFCD00037128
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₄H₂₁NO₄
Molecular Weight 387.43
Synonym(s) None
SMILES O=C(O)[C@H](CC1=CC=CC=C1)NC(OCC2C3=C(C4=C2C=CC=C4)C=CC=C3)=O

Description

Fmoc-Phe-OH is a bench-stable, moisture-tolerant amino acid derivative featuring a fluorenylmethoxy carbonyl (Fmoc) protecting group. This compound integrates seamlessly into solid-phase peptide synthesis workflows, enabling efficient chain elongation through selective coupling and facile deprotection under mild basic conditions.

Synthesis

Route1
- 63-91-2
- 28920-43-6
- ~83%
- In-stock
  
  35661-40-6
References
- Ishiyama, Haruaki; Yoshizawa, Kazuaki; Kobayashi, Jun'ichi Tetrahedron, 2012 , vol. 68, # 31 p. 6186 - 6192
Route2
- In-stock
  
  129397-83-7
- ~87%
- In-stock
  
  35661-40-6
References
- De Luca, Lidia; Giacomelli, Giampaolo; Masala, Simonetta; Porcheddu, Andrea Journal of Organic Chemistry, 2003 , vol. 68, # 12 p. 4999 - 5001
Route3
- 63-91-2
- In-stock
  
  82911-69-1
- ~95%
- In-stock
  
  35661-40-6
References
- Raydnov, M. G.; Klimenko, L. V.; Mitin, Yu. V. Russian Journal of Bioorganic Chemistry, 1999 , vol. 25, # 5 p. 283 - 287 Bioorganicheskaya Khimiya, 1999 , vol. 25, # 5 p. 323 - 328

Safety Information

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GHS Pictogram : N/A	GHS No : N/A
Signal Word : N/A	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

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Computational Chemistry Data

TPSA 75.63
LogP 4.221
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 6

Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Phenylalanine and derivatives

Building Blocks Functional Group Fmoc

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Amino Acid Derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids N-Protected Amino Acids

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Fmoc-Phe-OH

CAS No. 35661-40-6

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