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CS-W001157 4
Total: USD 88.00

(S)-2-((tert-Butoxycarbonyl)amino)pent-4-ynoic acid

  • CAS No. 63039-48-5

  • Cat. No. CS-W014975
  • Purity≥97%
  • MDL No.MFCD01320855

*For research and further manufacturing use only, not for direct human use.

(S)-2-((tert-Butoxycarbonyl)amino)pent-4-ynoic acid|CS-W014975

Structure of 63039-48-5

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General Information

  • CAS No. 63039-48-5
  • Cat. No. CS-W014975
  • Purity ≥97%
  • MDL No. MFCD01320855
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₅NO₄
  • Molecular Weight 213.23
  • Synonym(s) None
  • SMILES C#CC[C@@H](C(O)=O)NC(OC(C)(C)C)=O

Description

(S)-2-((tert-Butoxycarbonyl)amino)pent-4-ynoic acid features a chiral center and a terminal alkyne, enabling site-specific conjugation in bioconjugation workflows. The Boc-protected amine ensures stability during synthesis, while the alkyne moiety facilitates efficient copper-catalyzed azide-alkyne cycloaddition. This bifunctional scaffold supports modular peptide extension and probe integration under standard conditions.

Application

(S)-2-((tert-Butoxycarbonyl)amino)pent-4-ynoic acid serves as a versatile chiral building block for peptide synthesis and heterocycle construction. The protected amine and terminal alkyne functionalities enable orthogonal reactivity in coupling reactions, while the tert-butyl carbamate group offers excellent bench stability and straightforward deprotection. This compound facilitates efficient access to peptidomimetics and functionalized scaffolds via CuAAC or Sonogashira coupling, with high compatibility in standard synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H317
Precautionary Statements : P261-P272-P280-P302+P352-P363-P501

Quality Control

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   0.9876
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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