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CS-W001157 4
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(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-acetamidopropanoic acid

  • CAS No. 181952-29-4

  • Cat. No. CS-0162109
  • Purity≥97%
  • MDL No.MFCD15141989

*For research and further manufacturing use only, not for direct human use.

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-acetamidopropanoic acid|CS-0162109

Structure of 181952-29-4

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General Information

  • CAS No. 181952-29-4
  • Cat. No. CS-0162109
  • Purity ≥97%
  • MDL No. MFCD15141989
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₀H₂₀N₂O₅
  • Molecular Weight 368.38
  • Synonym(s) 3-(Acetylamino)-N-Fmoc-L-alanine
  • SMILES O=C(O)[C@@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)CNC(C)=O

Description

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-acetamidopropanoic acid serves as a protected amino acid derivative for peptide synthesis, featuring a fluorenylmethoxycarbonyl (Fmoc) group for orthogonal protection and an acetamido side chain enabling selective functionalization. This stable, bench-ready building block integrates seamlessly into automated and manual coupling protocols.

Application

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-acetamidopropanoic acid serves as a protected derivative of (S)-homophenylalanine, enabling efficient incorporation into peptide chains via standard solid-phase synthesis. The Fmoc group provides orthogonal protection for the amine, while the acetamide side chain offers enhanced stability and solubility. Its bench-stable nature and compatibility with diverse coupling conditions facilitate reliable use in the construction of complex peptide scaffolds and bioactive molecules.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P302+P352-P304+P340

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Computational Chemistry Data

  • TPSA   104.73
  • LogP   2.1144
  • H_Acceptors   4
  • H_Donors   3
  • Rotatable_Bonds   6

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