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CS-W001157 4
Total: USD 88.00

(R)-2-Hydroxymethylmorpholine hydrochloride

  • CAS No. 1436436-17-7

  • Cat. No. CS-W003761
  • Purity≥97%
  • MDL No.MFCD11052541

*For research and further manufacturing use only, not for direct human use.

(R)-2-Hydroxymethylmorpholine hydrochloride|CS-W003761

Structure of 1436436-17-7

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General Information

  • CAS No. 1436436-17-7
  • Cat. No. CS-W003761
  • Purity ≥97%
  • MDL No. MFCD11052541
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₂ClNO₂
  • Molecular Weight 153.61
  • Synonym(s) (R)-2-MorpholineMethanol HCl
  • SMILES OC[C@H]1CNCCO1.Cl

Description

(R)-2-Hydroxymethylmorpholine hydrochloride is a bench-stable chiral building block featuring a stereodefined hydroxymethyl group on the morpholine ring. This configuration enables selective functionalization in asymmetric synthesis, particularly in medicinal chemistry applications requiring precise stereocontrol. The hydrochloride salt enhances solubility and handling stability under standard conditions.

Application

(R)-2-Hydroxymethylmorpholine hydrochloride serves as a versatile chiral building block in medicinal chemistry, enabling efficient access to morpholine-based scaffolds. Its hydroxymethyl group facilitates downstream functionalization via oxidation, protection, or coupling reactions, while the protonated amine enhances solubility and simplifies purification. The compound exhibits excellent bench stability and functions reliably in standard synthetic workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   41.49
  • LogP   -0.6111
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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