(R)-Morpholin-3-ylmethanol hydrochloride

Name: (R)-Morpholin-3-ylmethanol hydrochloride
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CAS No. 1212377-10-0
Cat. No. CS-W018991
Purity≥97%
MDL No.MFCD09910295

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(R)-Morpholin-3-ylmethanol hydrochloride|CS-W018991

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General Information

CAS No. 1212377-10-0
Cat. No. CS-W018991
Purity ≥97%
MDL No. MFCD09910295
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₁₂ClNO₂
Molecular Weight 153.61
Synonym(s) R -Morpholin-3-ylMethanol hydrochloride
SMILES OC[C@@H]1COCCN1.[H]Cl

Description

(R)-Morpholin-3-ylmethanol hydrochloride is a bench-stable, moisture-tolerant chiral building block featuring a stereodefined hydroxymethyl group attached to the morpholine ring. This configuration enables selective incorporation into bioactive molecules and complex synthetic intermediates, where precise stereochemistry is essential. The hydrochloride salt enhances solubility in polar solvents, facilitating handling and integration into diverse reaction sequences.

Application

(R)-Morpholin-3-ylmethanol hydrochloride serves as a versatile chiral building block in medicinal chemistry, enabling efficient access to morpholine-containing scaffolds. Its well-defined stereochemistry and bench-stable hydrochloride salt facilitate handling and purification. The primary alcohol functionality supports diverse transformations—including derivatization, protection, and coupling reactions—making it suitable for constructing bioactive molecules and API intermediates with high reproducibility.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 41.49
LogP -0.6111
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Aliphatic heterocycle compounds Morpholine compounds

Key Words

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(R)-Morpholin-3-ylmethanol hydrochloride

CAS No. 1212377-10-0

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