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CS-W001157 4
Total: USD 88.00

(R)-3-Hydroxymethylmorpholine

  • CAS No. 211053-49-5

  • Cat. No. CS-0034507
  • Purity≥95%
  • MDL No.MFCD06799479

*For research and further manufacturing use only, not for direct human use.

(R)-3-Hydroxymethylmorpholine|CS-0034507

Structure of 211053-49-5

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General Information

  • CAS No. 211053-49-5
  • Cat. No. CS-0034507
  • Purity ≥95%
  • MDL No. MFCD06799479
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₁NO₂
  • Molecular Weight 117.15
  • Synonym(s) 3(R)-Hydroxymethylmorpholine
  • SMILES OC[C@@H]1COCCN1

Description

(R)-3-Hydroxymethylmorpholine is a chiral heterocyclic scaffold featuring a hydroxymethyl group at the 3-position, offering enhanced solubility and metabolic stability. This configuration enables selective incorporation into bioactive molecules, particularly in medicinal chemistry applications where stereocontrol is critical. The compound serves as a versatile building block for synthesizing targeted therapeutics and functional intermediates.

Synthesis

  • Route1

    References

    • ASTRAZENECA AB Patent: WO2006/137790 A1, 2006 ; Location in patent: Page/Page column 35 ; WO 2006/137790 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   41.49
  • LogP   -1.0329
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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