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CS-W001157 4
Total: USD 88.00

rel-(2R,6R)-2,6-Dimethylmorpholine

  • CAS No. 6485-45-6

  • Cat. No. CS-W005832
  • Purity≥96%
  • MDL No.MFCD09953181

*For research and further manufacturing use only, not for direct human use.

rel-(2R,6R)-2,6-Dimethylmorpholine|CS-W005832

Structure of 6485-45-6

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General Information

  • CAS No. 6485-45-6
  • Cat. No. CS-W005832
  • Purity ≥96%
  • MDL No. MFCD09953181
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₃NO
  • Molecular Weight 115.17
  • Synonym(s) (2S,6S)-2,6-dimethylmorpholine
  • SMILES C[C@H]1O[C@H](C)CNC1

Description

rel-(2R,6R)-2,6-Dimethylmorpholine is a chiral, bench-stable heterocycle featuring two methyl groups at the 2- and 6-positions of the morpholine ring. This stereochemistry imparts distinct conformational rigidity and enhanced solubility in polar organic solvents. The compound serves as a tailored building block in asymmetric synthesis, particularly for constructing nitrogen-containing scaffolds with defined spatial orientation. Its stability under standard conditions facilitates handling in process development workflows.

Application

rel-(2R,6R)-2,6-Dimethylmorpholine serves as a stereodefined, bench-stable heterocyclic building block for medicinal chemistry and catalysis. Its constrained conformation enhances rigidity in target molecules, improving binding selectivity. The tertiary amine functionality enables efficient salt formation and facilitates protonation in synthetic transformations. Exhibiting excellent functional group tolerance and compatibility with standard coupling reactions, it functions as a versatile scaffold in the synthesis of bioactive compounds and catalysts.

Safety Information

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GHS Pictogram :
GHS No : GHS02,GHS05,GHS06
Signal Word : Danger
UN#: 1992
Class : 3 (6.1)
Packing Group : Ⅲ
Hazard Statements : H226-H311-H318
Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501

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Computational Chemistry Data

  • TPSA   21.26
  • LogP   0.3832
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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