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CS-W001157 4
Total: USD 88.00

cis-2,6-Dimethylmorpholine

  • CAS No. 6485-55-8

  • Cat. No. CS-0008437
  • Purity≥98%
  • MDL No.MFCD00078428

*For research and further manufacturing use only, not for direct human use.

cis-2,6-Dimethylmorpholine|CS-0008437

Structure of 6485-55-8

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General Information

  • CAS No. 6485-55-8
  • Cat. No. CS-0008437
  • Purity ≥98%
  • MDL No. MFCD00078428
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₃NO
  • Molecular Weight 115.17
  • Synonym(s) Dimethylmorpholine
  • SMILES C[C@@H]1O[C@H](C)CNC1

Description

cis-2,6-Dimethylmorpholine is a sterically hindered, bench-stable nitrogen heterocycle featuring a constrained cis-configuration that enhances its conformational rigidity. This structural feature imparts high nucleophilicity and improved selectivity in synthetic transformations. The molecule integrates readily into catalytic systems and serves as a tunable ligand scaffold for transition metal complexes. Its moisture-tolerant nature simplifies handling under standard laboratory conditions.

Application

cis-2,6-Dimethylmorpholine serves as a versatile, bench-stable nitrogen heterocycle enabling efficient amine-mediated transformations and serving as a key scaffold in medicinal chemistry. Its constrained conformation enhances hydrogen-bonding capacity and metabolic stability, while the tertiary amine functionality facilitates salt formation and solubility optimization in synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS02,GHS05,GHS06
Signal Word : Danger
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226-H311-H318
Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P302+P352-P370+P378-P405-P501

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Computational Chemistry Data

  • TPSA   21.26
  • LogP   0.3832
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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