(S)-Morpholin-2-ylmethanol

Name: (S)-Morpholin-2-ylmethanol
Brand: ChemScene
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CAS No. 132073-83-7
Cat. No. CS-0020036
Purity≥97%
MDL No.MFCD09260718

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Description

(S)-Morpholin-2-ylmethanol is a chiral building block featuring a morpholine ring fused to a primary alcohol group. This configuration enables selective incorporation into bioactive molecules, particularly in medicinal chemistry scaffolds requiring stereochemical control. The hydroxymethyl functionality facilitates downstream derivatization via esterification or ether formation. Stable under standard handling conditions and compatible with common organic solvents, it supports efficient integration into multi-step synthesis workflows without degradation.

Application

(S)-Morpholin-2-ylmethanol serves as a versatile chiral building block in medicinal chemistry, enabling the construction of bioactive heterocycles through established functional group transformations. Its morpholinylmethyl motif exhibits favorable solubility, metabolic stability, and hydrogen-bonding capacity, making it well-suited for drug discovery applications. The compound demonstrates excellent bench stability and compatibility with standard synthetic protocols, facilitating straightforward incorporation into complex molecular architectures.

General Information

CAS No. 132073-83-7
Cat. No. CS-0020036
Purity ≥97%
MDL No. MFCD09260718
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₁₁NO₂
Molecular Weight 117.15
Synonym(s) (2S)-2-Morpholinemethanol; (2S)-Morpholin-2-ylmethanol; (S)-1-Morpholin-2-ylmethanol; (S)-Morpholin-2-ylmethanol; (S)-Morpholine-2-methanol; (S)-morpholin-2-ylmethanol HCL
SMILES OC[C@@H]1CNCCO1

Computational Chemistry Data

TPSA 41.49
LogP -1.0329
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Morpholine compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(S)-Morpholin-2-ylmethanol

CAS No. 132073-83-7

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