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Structure of 10315-07-8
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1-Benzylpiperidine-4-carboxylic acid features a rigid, electron-rich piperidine core functionalized with a benzyl group and a carboxylic acid at the 4-position. This combination enables direct integration into bioactive scaffolds, offering enhanced solubility and metabolic stability in medicinal chemistry applications.
1-Benzylpiperidine-4-carboxylic acid serves as a versatile scaffold for medicinal chemistry campaigns, enabling the construction of bioactive heterocycles through standard amide coupling and reduction protocols. Its benzylated piperidine core provides enhanced metabolic stability and favorable lipophilicity, while the carboxylic acid group facilitates direct conjugation or derivatization in peptide and macrocyclic synthesis. The compound exhibits good bench stability and is readily purified by recrystallization or flash chromatography.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: