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CS-W001157 4
Total: USD 88.00

1-(2,2,2-Trifluoroacetyl)piperidine-4-carboxylic acid

  • CAS No. 126501-70-0

  • Cat. No. CS-0038986
  • Purity≥95%
  • MDL No.MFCD03840837

*For research and further manufacturing use only, not for direct human use.

1-(2,2,2-Trifluoroacetyl)piperidine-4-carboxylic acid|CS-0038986

Structure of 126501-70-0

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General Information

  • CAS No. 126501-70-0
  • Cat. No. CS-0038986
  • Purity ≥95%
  • MDL No. MFCD03840837
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀F₃NO₃
  • Molecular Weight 225.17
  • Synonym(s) 1-(Trifluoroacetyl)piperidine-4-carboxylic acid
  • SMILES C1CN(CCC1C(=O)O)C(=O)C(F)(F)F

Synthesis

  • Route1
    • Piperidine-4-carboxylic acid Avatrombopag Impurity|CS-0377512
      498-94-2
    • null|null
      358-23-6
    • ~70%
    • In-stock
      1-(2,2,2-Trifluoroacetyl)piperidine-4-carboxylic acid|CS-0038986
      126501-70-0

    References

    • ABBOTT LABORATORIES; ABBOTT LABORATORIES TRADING (SHANGHAI) COMPANY, LTD.; WANG, Xueqing; MEYER, Michael; YAO, Betty; GUO, Tao; WEI, Guo Ping,Robert; WANG, Lijuan, Jane Patent: WO2013/10453 A1, 2013 ; Location in patent: Page/Page column 109 ;
  • Route2
    • Piperidine-4-carboxylic acid Avatrombopag Impurity|CS-0377512
      498-94-2
    • null|null
      407-25-0
    • ~73%
    • In-stock
      1-(2,2,2-Trifluoroacetyl)piperidine-4-carboxylic acid|CS-0038986
      126501-70-0

    References

    • Hibert; Hoffmann; Miller; Carr Journal of Medicinal Chemistry, 1990 , vol. 33, # 6 p. 1594 - 1600

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   57.61
  • LogP   0.8719
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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