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CS-W001157 4
Total: USD 88.00

1-Methylpiperidine-4-carboxylic acid hydrochloride

  • CAS No. 71985-80-3

  • Cat. No. CS-W004085
  • Purity≥97%
  • MDL No.MFCD00190235

*For research and further manufacturing use only, not for direct human use.

1-Methylpiperidine-4-carboxylic acid hydrochloride|CS-W004085

Structure of 71985-80-3

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General Information

  • CAS No. 71985-80-3
  • Cat. No. CS-W004085
  • Purity ≥97%
  • MDL No. MFCD00190235
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₄ClNO₂
  • Molecular Weight 179.64
  • Synonym(s) N-Methyl isonipecotic acid hydrochloride; 1-Methylpiperidine-4-carboxylic acid hydrochloride
  • SMILES OC(C1CCN(C)CC1)=O.Cl

Description

1-Methylpiperidine-4-carboxylic acid hydrochloride features a rigid, nitrogen-rich heterocyclic core with a strategically positioned carboxylic acid and methyl group. This configuration enhances solubility and stability under standard conditions, enabling efficient incorporation into peptide-like scaffolds and bioactive molecule design.

Synthesis

  • Route1
    • Piperidine-4-carboxylic acid Avatrombopag Impurity|CS-0377512
      498-94-2
    • null|null
      50-00-0
    • ~96%
    • In-stock
      1-Methylpiperidine-4-carboxylic acid hydrochloride|CS-W004085
      71985-80-3

    References

    • Gray, Allan P.; Platz, Robert D.; Henderson, Theresa R.; Chang, Timothy C. P.; Takahashi, Kazuyuki; Dretchen, Kenneth L. Journal of Medicinal Chemistry, 1988 , vol. 31, # 4 p. 807 - 814
  • Route2

    References

    • F2G LIMITED Patent: US2011/9390 A1, 2011 ; Location in patent: Page/Page column 14 ;
  • Route3
    • Piperidine-4-carboxylic acid Avatrombopag Impurity|CS-0377512
      498-94-2
    • ~%
    • In-stock
      1-Methylpiperidine-4-carboxylic acid hydrochloride|CS-W004085
      71985-80-3
    • null|null
      50675-21-3

    References

    • US4757079 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   40.54
  • LogP   0.8346
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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