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CS-W001157 4
Total: USD 88.00

Methyl 1-methylpiperidine-4-carboxylate

  • CAS No. 1690-75-1

  • Cat. No. CS-0020079
  • Purity≥98%
  • MDL No.MFCD06658483

*For research and further manufacturing use only, not for direct human use.

Methyl 1-methylpiperidine-4-carboxylate|CS-0020079

Structure of 1690-75-1

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General Information

  • CAS No. 1690-75-1
  • Cat. No. CS-0020079
  • Purity ≥98%
  • MDL No. MFCD06658483
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₅NO₂
  • Molecular Weight 157.21
  • Synonym(s) Methyl N-methylisonipecotinate; N-Methylpiperidine-4-Carboxylic Acid Methyl Ester
  • SMILES O=C(C1CCN(C)CC1)OC

Description

Methyl 1-methylpiperidine-4-carboxylate features a sterically hindered piperidine core with a methylated nitrogen and a pendant ester group. This configuration enhances solubility in organic solvents while maintaining stability under standard bench conditions. The molecule serves as a key intermediate in the synthesis of bioactive alkaloids and pharmaceutical candidates, particularly where modulated basicity and metabolic resistance are required.

Application

Methyl 1-methylpiperidine-4-carboxylate serves as a versatile building block in medicinal chemistry, enabling efficient access to piperidine-based scaffolds common in bioactive molecules. Its methyl ester group facilitates straightforward functionalization via hydrolysis or reduction, while the tertiary amine center offers robust compatibility with standard coupling and derivatization protocols. The compound exhibits excellent bench stability and ease of purification, making it well-suited for iterative synthesis campaigns and API intermediate development.

Safety Information

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GHS Pictogram :
GHS No : GHS02,GHS05
Signal Word : Danger
UN#: 3265
Class : 8
Packing Group : Ⅱ
Hazard Statements : H225-H314
Precautionary Statements : P210-P240-P241-P280-P370+P378

Quality Control

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Computational Chemistry Data

  • TPSA   29.54
  • LogP   0.5012
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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