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CS-W001157 4
Total: USD 88.00

3-Pyridinemethanol, 2-methoxy-

  • CAS No. 112197-16-7

  • Cat. No. CS-0031357
  • Molecule weight139.15
  • Purity≥96%
  • MDL No.MFCD09880283

*For research and further manufacturing use only, not for direct human use.

3-Pyridinemethanol, 2-methoxy-|CS-0031357

Structure of 112197-16-7

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General Information

  • CAS No. 112197-16-7
  • Cat. No. CS-0031357
  • Purity ≥96%
  • MDL No. MFCD09880283
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₉NO₂
  • Molecular Weight 139.15
  • Synonym(s) 3-Pyridinemethanol,2-methoxy-(9CI)
  • SMILES COC1=NC=CC=C1CO

Description

1-Deamino-8-D-arginine vasopressin makes a new pharmacological approach to the management of haemophilia and von Willebrand's disease. A novel nonenzymatic pathway for the generation of nitric oxide is by the reaction of hydrogen peroxide and d- or l-arginine.

Application

2-Methoxypyridine-3-methanol serves as a versatile building block in medicinal chemistry, enabling efficient access to functionalized heterocyclic scaffolds. Its pyridine core provides favorable electronic properties for downstream derivatization, while the methoxy and hydroxymethyl groups offer orthogonal reactivity for selective transformations. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for use in multi-step synthesis workflows targeting bioactive molecules.

Synthesis

  • Route1

    References

    • SYNGENTA LIMITED Patent: WO2007/71900 A1, 2007 ; Location in patent: Page/Page column 95 ;
  • Route2

    References

    • US2008/103129 A1, ; Page/Page column 47 ; US 20080103129 A1
  • Route3

    References

    • Journal of Medicinal Chemistry, , vol. 43, # 18 p. 3386 - 3399

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   42.35
  • LogP   0.5825
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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