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CS-W001157 4
Total: USD 88.00

2-Methoxy-3-pyridinecarboxaldehyde

  • CAS No. 71255-09-9

  • Cat. No. CS-W004144
  • Purity≥96%
  • MDL No.MFCD04115112

*For research and further manufacturing use only, not for direct human use.

2-Methoxy-3-pyridinecarboxaldehyde|CS-W004144

Structure of 71255-09-9

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General Information

  • CAS No. 71255-09-9
  • Cat. No. CS-W004144
  • Purity ≥96%
  • MDL No. MFCD04115112
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇NO₂
  • Molecular Weight 137.14
  • Synonym(s) 3-Pyridinecarboxaldehyde, 2-methoxy-
  • SMILES COc1ncccc1C=O

Description

2-Methoxy-3-pyridinecarboxaldehyde delivers a pyridine scaffold with orthogonal functional handles: a methoxy group at the 2-position and an aldehyde at the 3-position. This configuration enables direct coupling in cross-coupling reactions or imine formation, offering high reactivity under mild conditions. The electron-deficient aldehyde is stabilized by the adjacent nitrogen, enhancing shelf stability and compatibility with sensitive reaction systems.

Synthesis

  • Route1
    • In-stock
      3-Bromo-2-methoxypyridine|CS-D0942
      13472-59-8
    • null|null
      68-12-2
    • ~87%
    • In-stock
      2-Methoxy-3-pyridinecarboxaldehyde|CS-W004144
      71255-09-9

    References

    • Struk, Lukasz; Sosnicki, Jacek G. Synthesis, 2012 , vol. 44, # 5 p. 735 - 746
  • Route2
    • null|null
      1628-89-3
    • null|null
      109-72-8
    • null|null
      68-12-2
    • ~40%
    • In-stock
      2-Methoxy-3-pyridinecarboxaldehyde|CS-W004144
      71255-09-9
    • null|null
      112219-56-4

    References

    • Trecourt, F.; Mallet, M.; Marsais, F.; Queguiner, G. Journal of Organic Chemistry, 1988 , vol. 53, # 7 p. 1367 - 1371
  • Route3
    • null|null
      1628-89-3
    • null|null
      68-12-2
    • ~%
    • In-stock
      2-Methoxy-3-pyridinecarboxaldehyde|CS-W004144
      71255-09-9

    References

    • Journal of Organic Chemistry, , vol. 55, # 1 p. 69 - 73

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   39.19
  • LogP   0.9027
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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