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CS-W001157 4
Total: USD 88.00

Propargyl-PEG2-amine

  • CAS No. 944561-44-8

  • Cat. No. CS-0044012
  • Purity≥97%
  • MDL No.MFCD19160595

*For research and further manufacturing use only, not for direct human use.

Propargyl-PEG2-amine|CS-0044012

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General Information

  • CAS No. 944561-44-8
  • Cat. No. CS-0044012
  • Purity ≥97%
  • MDL No. MFCD19160595
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₃NO₂
  • Molecular Weight 143.18
  • Synonym(s) None
  • SMILES NCCOCCOCC#C

Description

Propargyl-PEG2-amine features a reactive alkyne handle flanked by two ethylene glycol units, enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC). This bifunctional linker combines excellent water solubility with stable conjugation chemistry, ideal for bioconjugation and surface functionalization in aqueous environments.

Application

Propargyl-PEG2-amine serves as a versatile bifunctional linker for conjugation chemistries, enabling efficient CuAAC reactions via its terminal alkyne group while providing a primary amine for orthogonal coupling. Its short PEG spacer enhances solubility and reduces steric hindrance, facilitating reliable bioconjugation in peptide, oligonucleotide, and antibody labeling workflows. The compound exhibits excellent bench stability and is compatible with standard purification methods.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   44.48
  • LogP   -0.3885
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   6

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