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CS-W001157 4
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Propargyl-PEG3-amine

  • CAS No. 932741-19-0

  • Cat. No. CS-0114325
  • Purity≥96%
  • MDL No.MFCD20720810

*For research and further manufacturing use only, not for direct human use.

Propargyl-PEG3-amine|CS-0114325

Structure of 932741-19-0

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General Information

  • CAS No. 932741-19-0
  • Cat. No. CS-0114325
  • Purity ≥96%
  • MDL No. MFCD20720810
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₇NO₃
  • Molecular Weight 187.24
  • Synonym(s) None
  • SMILES C#CCOCCOCCOCCN

Description

Propargyl-PEG3-amine is a bifunctional linker featuring a terminal alkyne for click chemistry and a primary amine for conjugation. This water-soluble, bench-stable reagent integrates seamlessly into bioconjugation workflows, enabling efficient coupling via copper-catalyzed or strain-promoted azide-alkyne cycloaddition.

Application

Propargyl-PEG3-amine serves as a versatile bifunctional linker for bioconjugation and polymer chemistry, combining the reactive terminal alkyne with a stable, hydrophilic PEG3 spacer. It enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) for site-specific conjugation, while the amine group facilitates coupling to carboxylate or activated ester functionalities. Its excellent solubility, bench stability, and ease of purification make it ideal for synthesizing peptide-PEG-protein conjugates, drug delivery systems, and functionalized surfaces in high-throughput workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   53.71
  • LogP   -0.3719
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   9

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