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CS-W001157 4
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Propargyl-PEG5-amine

  • CAS No. 1589522-46-2

  • Cat. No. CS-0109024
  • Molecule weight275.34
  • Purity≥95%
  • MDL No.MFCD27977505

*For research and further manufacturing use only, not for direct human use.

Propargyl-PEG5-amine|CS-0109024

Structure of 1589522-46-2

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General Information

  • CAS No. 1589522-46-2
  • Cat. No. CS-0109024
  • Purity ≥95%
  • MDL No. MFCD27977505
  • Storage -20°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₅NO₅
  • Molecular Weight 275.34
  • Synonym(s) None
  • SMILES C#CCOCCOCCOCCOCCOCCN

Description

Propargyl-PEG5-amine is a water-soluble, bifunctional linker featuring a terminal alkyne for copper-catalyzed click chemistry and a primary amine for conjugation. This PEG5 spacer provides enhanced solubility and reduced aggregation in biological environments, enabling efficient bioconjugation workflows with minimal steric interference.

Application

Propargyl-PEG5-amine serves as a versatile bifunctional linker for conjugation and polymer functionalization. The terminal alkyne enables efficient copper-catalyzed azide–alkyne cycloaddition (CuAAC), while the primary amine facilitates amide coupling or Michael addition. Its PEG5 spacer provides enhanced solubility and reduced aggregation, making it ideal for bioconjugation, probe synthesis, and surface modification in aqueous environments.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

Quality Control

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Computational Chemistry Data

  • TPSA   72.17
  • LogP   -0.3387
  • H_Acceptors   6
  • H_Donors   1
  • Rotatable_Bonds   15

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