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*For research and further manufacturing use only, not for direct human use.
Structure of 170908-81-3
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DOTA-NHS-ester features a reactive NHS ester group enabling efficient conjugation to primary amines under physiological conditions. This bifunctional chelator integrates seamlessly into bioconjugation workflows, delivering stable metal coordination for imaging and therapeutic applications.
DOTA-NHS-ester serves as a robust bifunctional linker for conjugating chelating agents to biomolecules. It enables efficient amine-directed coupling under physiological conditions, facilitating the site-specific attachment of radiometals or fluorescent labels to proteins, antibodies, and peptides. The stable DOTA core ensures high metal affinity, while the NHS ester provides excellent reactivity with primary amines, offering predictable conjugation yields and simplified purification via dialysis or size exclusion.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362
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Lot numbers can be found on the outside label of a product: