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NH2-C2-NH-Boc

  • CAS No. 57260-73-8

  • Cat. No. CS-B0430
  • Purity≥96%
  • MDL No.MFCD00191871

*For research and further manufacturing use only, not for direct human use.

NH2-C2-NH-Boc|CS-B0430

Structure of 57260-73-8

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General Information

  • CAS No. 57260-73-8
  • Cat. No. CS-B0430
  • Purity ≥96%
  • MDL No. MFCD00191871
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₆N₂O₂
  • Molecular Weight 160.21
  • Synonym(s) PROTAC Linker 22
  • SMILES O=C(NCCN)OC(C)(C)C

Description

L-glutamine is an essential amino acid that is a crucial component of culture media that serves as a major energy source for cells in culture. L-glutamine is very stable as a dry powder and as a frozen solution. In liquid media or stock solutions, however, L-glutamine degrades relatively rapidly. Optimal cell performance usually requires supplementation of the media with L-glutamine prior to use.L-glutamine is an essential amino acid that is a crucial component of culture media, which serves as a major energy source for cells in culture. Optimal cell performance usually requires supplementation of the medium with L-glutamine prior to use.

Application

NH₂–C₂–NH–Boc serves as a versatile diaminobutane building block for the synthesis of heterocyclic scaffolds and peptide mimetics. Its bifunctional amine architecture enables sequential coupling reactions with carboxylic acids, isocyanates, and electrophiles, while the Boc group provides stable protection under standard synthetic conditions. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for iterative solid-phase and solution-phase synthesis in medicinal chemistry workflows.

Synthesis

  • Route1
    • In-stock
      Di-tert-butyl dicarbonate|CS-0017817
      24424-99-5
    • null|null
      107-15-3
    • ~99%
    • In-stock
      NH2-C2-NH-Boc|CS-B0430
      57260-73-8

    References

    • Jensen, Kim B.; Braxmeier, Tobias M.; Demarcus, Mariangela; Frey, Jeremy G.; Kilburn, Jeremy D. Chemistry - A European Journal, 2002 , vol. 8, # 6 p. 1300 - 1309 Title/Abstract Full Text View citing articles Show Details Wang, Jun; Uttamchandani, Mahesh; Li, Junqi; Hu, Mingyu; Yao, Shao Q. Chemical Communications, 2006 , # 36 p. 3783 - 3785
  • Route2

    References

    • Merrell Pharmaceuticals Inc. Patent: US5604221 A1, 1997 ;
  • Route3

    References

    • Ravikumar Synthetic Communications, 1994 , vol. 24, # 12 p. 1767 - 1772

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

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Computational Chemistry Data

  • TPSA   64.35
  • LogP   0.4698
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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