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CS-W001157 4
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Propargyl-PEG6-NH2

  • CAS No. 1198080-04-4

  • Cat. No. CS-0105428
  • Purity≥97%
  • MDL No.MFCD29042376

*For research and further manufacturing use only, not for direct human use.

Propargyl-PEG6-NH2|CS-0105428

Structure of 1198080-04-4

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General Information

  • CAS No. 1198080-04-4
  • Cat. No. CS-0105428
  • Purity ≥97%
  • MDL No. MFCD29042376
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₂₉NO₆
  • Molecular Weight 319.39
  • Synonym(s) None
  • SMILES C#CCOCCOCCOCCOCCOCCOCCN

Description

Propargyl-PEG6-NH2 features a terminal alkyne group flanked by a six-ethylene glycol spacer and a primary amine, enabling bioorthogonal conjugation via copper-catalyzed azide-alkyne cycloaddition. This bifunctional scaffold integrates seamlessly into peptide and protein modifications, offering enhanced solubility and stability under physiological conditions.

Application

Propargyl-PEG6-NH₂ serves as a versatile bifunctional linker for bioconjugation and polymer chemistry, combining a terminal alkyne for copper-catalyzed azide-alkyne cycloaddition (CuAAC) with a primary amine for amide coupling. The six-ethylene glycol units provide enhanced solubility and reduced non-specific binding, while the propargyl group ensures efficient, selective conjugation under mild conditions. Ideal for peptide modification, probe synthesis, and functionalizing biomaterials.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319
Precautionary Statements : P264-P270-P280-P302+P352-P330-P362+P364-P501

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Computational Chemistry Data

  • TPSA   81.4
  • LogP   -0.3221
  • H_Acceptors   7
  • H_Donors   1
  • Rotatable_Bonds   18

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