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Structure of 911466-96-1
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2-(Ethoxycarbonyl)thiazole-4-carboxylic acid features a thiazole scaffold bearing both ethoxycarbonyl and carboxylic acid functionalities, enabling direct integration into heterocyclic synthesis. The electron-deficient ring facilitates nucleophilic substitution, while the orthogonal polar groups support conjugation in bioactive molecule design. This bench-stable reagent streamlines access to functionalized thiazoles under standard conditions.
2-(Ethoxycarbonyl)thiazole-4-carboxylic acid serves as a versatile building block for heterocyclic synthesis, enabling efficient access to thiazole-based scaffolds through standard amidation, esterification, and decarboxylation protocols. Its dual electrophilic (carboxylate and carbonyl) functionalities tolerate diverse reaction conditions and facilitate downstream derivatization in medicinal chemistry workflows. The ethoxycarbonyl group enhances solubility and simplifies purification, while the intact thiazole ring ensures structural stability under common bench-scale transformations.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: