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Structure of 884494-76-2
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6-Chloro-3-fluoropicolinic acid features a strategically positioned chloro and fluoro substituent on the picolinic acid scaffold, enhancing electron deficiency and metabolic stability. This configuration supports efficient incorporation into bioactive heterocycles, particularly in kinase inhibitors and pharmaceutical intermediates requiring polar, rigid scaffolds under standard conditions.
6-Chloro-3-fluoropicolinic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-halogenated pyridine core facilitates cross-coupling reactions and nucleophilic substitution, while the carboxylic acid group supports direct derivatization. The compound exhibits excellent bench stability and compatibility with standard purification methods, making it ideal for scalable synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: