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CS-W001157 4
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(R)-But-3-yn-2-amine hydrochloride

  • CAS No. 869349-15-5

  • Cat. No. CS-0147129
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(R)-But-3-yn-2-amine hydrochloride|CS-0147129

Structure of 869349-15-5

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General Information

  • CAS No. 869349-15-5
  • Cat. No. CS-0147129
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₈ClN
  • Molecular Weight 105.57
  • Synonym(s) (R)-1-Methyl-prop-2-ynylamine hydrochloride
  • SMILES N[C@H](C)C#C.[H]Cl

Description

(R)-But-3-yn-2-amine hydrochloride is a chiral alkyne-containing amine featuring a stereodefined (R) configuration at the C2 position. This bench-stable, moisture-tolerant compound integrates readily into synthetic sequences requiring both nucleophilic amine and reactive terminal alkyne functionalities. Its hydrochloride salt form enhances solubility in polar solvents, facilitating use in peptide coupling, transition-metal-catalyzed cross-couplings, and click chemistry applications.

Application

(R)-But-3-yn-2-amine hydrochloride serves as a versatile chiral building block for the synthesis of functionalized alkynes and nitrogen-containing heterocycles. Its terminal alkyne functionality enables efficient copper-catalyzed coupling reactions, while the amine group offers facile derivatization and protection. The hydrochloride salt enhances solubility and stability, facilitating handling and purification in standard organic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H317
Precautionary Statements : P261-P272-P280-P302+P352-P363-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   0.3886
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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