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CS-W001157 4
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(S)-But-3-yn-2-amine hydrochloride

  • CAS No. 1414960-66-9

  • Cat. No. CS-0147130
  • Molecule weight105.57
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S)-But-3-yn-2-amine hydrochloride|CS-0147130

Structure of 1414960-66-9

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General Information

  • CAS No. 1414960-66-9
  • Cat. No. CS-0147130
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₈ClN
  • Molecular Weight 105.57
  • Synonym(s) (S)-1-Methyl-prop-2-ynylamine hydrochloride
  • SMILES N[C@@H](C)C#C.[H]Cl

Description

(S)-But-3-yn-2-amine hydrochloride is a chiral building block featuring a terminal alkyne and primary amine functional group, enabling efficient coupling in transition-metal-catalyzed transformations. This bench-stable salt facilitates direct incorporation into peptide-like scaffolds and conjugation workflows.

Application

(S)-But-3-yn-2-amine hydrochloride serves as a valuable chiral building block for the synthesis of functionalized pyrrolidines and other nitrogen-containing heterocycles. Its terminal alkyne and primary amine functionalities enable diverse transformations, including copper-catalyzed azide-alkyne cycloadditions and transition-metal-mediated couplings. The hydrochloride salt enhances bench stability and simplifies purification, making it well-suited for use in medicinal chemistry campaigns and process-scale applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H317
Precautionary Statements : P261-P272-P280-P302+P352-P363-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   0.3886
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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