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CS-W001157 4
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Hex-5-yn-1-amine hydrochloride

  • CAS No. 102169-54-0

  • Cat. No. CS-0059697
  • Purity≥97%
  • MDL No.MFCD18839147

*For research and further manufacturing use only, not for direct human use.

Hex-5-yn-1-amine hydrochloride|CS-0059697

Structure of 102169-54-0

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General Information

  • CAS No. 102169-54-0
  • Cat. No. CS-0059697
  • Purity ≥97%
  • MDL No. MFCD18839147
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₂ClN
  • Molecular Weight 133.62
  • Synonym(s) None
  • SMILES Cl.C#CCCCCN

Description

Hex-5-yn-1-amine hydrochloride offers a terminal alkyne handle for copper-catalyzed azide-alkyne cycloaddition, enabling efficient conjugation in bioorthogonal labeling. The amine functionality facilitates derivatization, while the hydrochloride salt ensures high solubility and stability under standard bench conditions.

Application

Hex-5-yn-1-amine hydrochloride serves as a versatile synthetic building block for the construction of nitrogen-containing heterocycles and functionalized alkenes. Its terminal alkyne and primary amine functionalities enable efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) and straightforward derivatization via amine coupling reactions. The hydrochloride salt form enhances bench stability and simplifies handling, facilitating purification and integration into multistep synthesis workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   1.1704
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   3

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