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CS-W001157 4
Total: USD 88.00

Estradiol

  • CAS No. 50-28-2

  • Cat. No. CS-1938
  • Purity≥98%
  • MDL No.MFCD00003693

*For research and further manufacturing use only, not for direct human use.

Estradiol|CS-1938

Structure of 50-28-2

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General Information

  • CAS No. 50-28-2
  • Cat. No. CS-1938
  • Purity ≥98%
  • MDL No. MFCD00003693
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₈H₂₄O₂
  • Molecular Weight None
  • Synonym(s) β-Estradiol; E2; 17β-Estradiol; 17β-Oestradiol
  • SMILES C[C@@]1([C@H]2O)[C@](CC2)([H])[C@@](CCC3=C4C=CC(O)=C3)([H])[C@]4([H])CC1

Description

Reagent used for the stereoselective preparation of N-[1-(cyanomethylaminocarbonyl)-2-arylethyl]arylamides used as Cathepsin inhibitors

Synthesis

  • Route1
    • null|null
      250331-30-7
    • ~81%
    • In-stock
      Estradiol|CS-1938
      50-28-2

    References

    • Rigby, James H.; Warshakoon, Namal C.; Payen, Anne J. Journal of the American Chemical Society, 1999 , vol. 121, # 36 p. 8237 - 8245
  • Route2
    • null|null
      53-16-7
    • ~97%
    • In-stock
      Estradiol|CS-1938
      50-28-2

    References

    • Wang, Bijia; Qin, Linlin; Neumann, Kiel D.; Uppaluri, Shriharsha; Cerny, Ronald L.; DiMagno, Stephen G. Organic Letters, 2010 , vol. 12, # 15 p. 3352 - 3355
  • Route3
    • null|null
      846-48-0
    • ~%
    • In-stock
      Estradiol|CS-1938
      50-28-2

    References

    • Wilds; Djerassi Journal of the American Chemical Society, 1946 , vol. 68, p. 2125,2128 Full Text Show Details Inhoffen in H. Lettre; H. H. Inhoffen; R. Tschesche Ueber Sterine, Gallensaeuren und verwandte Naturstoffe, 2. Aufl. Bd. 2 <Stuttgart 1959> S. 641 Full Text Show Details Inhoffen Angewandte Chemie, 1947 , vol. 59, p. 207,211, 212 Full Text Show Details Schering Corp. Patent: US2361847 , 1941 ; Full Text Show Details Schering A.G. Patent: DE751739 , 1936 ; DRP/DRBP Org.Chem. Full Text Show Details Inhoffen; Zuehlsdorff Chemische Berichte, 1941 , vol. 74, p. 1911,1916

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS08,GHS09
Signal Word : Danger
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H351-H360-H362-H410
Precautionary Statements : P260-P263-P264-P270-P273-P280-P391-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   3.6092
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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