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CS-W001157 4
Total: USD 88.00

3-Furanoic acid

  • CAS No. 488-93-7

  • Cat. No. CS-D0170
  • Purity≥98%
  • MDL No.MFCD00005350

*For research and further manufacturing use only, not for direct human use.

3-Furanoic acid|CS-D0170

Structure of 488-93-7

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General Information

  • CAS No. 488-93-7
  • Cat. No. CS-D0170
  • Purity ≥98%
  • MDL No. MFCD00005350
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₄O₃
  • Molecular Weight 112.08
  • Synonym(s) None
  • SMILES O=C(O)C1=COC=C1

Description

3-Furoic acid can be used as a reactant to synthesize: Furan-2,5- and furan-2,4-dicarboxylic acid under solvent-free conditions via disproportionation reaction. ()-Hyperolactone A by reacting with 2-methylbutanal.Furo[2,3-b]pyridin-4-one-5-carboxylate ester derivatives as potential non-nucleoside inhibitors of human herpesvirus polymerases.

Application

3-Furanoic acid serves as a versatile building block in synthetic organic chemistry, enabling access to bioactive heterocycles and functionalized furan derivatives. Its carboxylic acid functionality facilitates direct amidation, esterification, and coupling reactions under standard conditions. The molecule exhibits good bench stability and mild reactivity, allowing for efficient incorporation into complex scaffolds with minimal protection requirements. It functions as a key intermediate in the synthesis of pharmaceutical candidates and agrochemicals requiring oxygen-rich heterocyclic motifs.

Synthesis

  • Route1
    • null|null
      22037-28-1
    • null|null
      201230-82-2
    • ~5%
    • In-stock
      3-Furanoic acid|CS-D0170
      488-93-7
    • In-stock
      Methyl furan-3-carboxylate|CS-0187526
      13129-23-2

    References

    • Marchal, Joel; Bodiguel, Jacques; Fort, Yves; Caubere, Paul Journal of Organic Chemistry, 1995 , vol. 60, # 26 p. 8336 - 8340
  • Route2

    References

    • Zhao, Junfeng; Mueck-Lichtenfeld, Christian; Studer, Armido Advanced Synthesis and Catalysis, 2013 , vol. 355, # 6 p. 1098 - 1106
  • Route3
    • null|null
      22037-28-1
    • null|null
      67-56-1
    • null|null
      201230-82-2
    • ~4%
    • In-stock
      3-Furanoic acid|CS-D0170
      488-93-7
    • In-stock
      Methyl furan-3-carboxylate|CS-0187526
      13129-23-2

    References

    • Marchal, Joel; Bodiguel, Jacques; Fort, Yves; Caubere, Paul Journal of Organic Chemistry, 1995 , vol. 60, # 26 p. 8336 - 8340

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

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Computational Chemistry Data

  • TPSA   50.44
  • LogP   0.9778
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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