2-Amino-N-(prop-2-yn-1-yl)acetamide hydrochloride

Name: 2-Amino-N-(prop-2-yn-1-yl)acetamide hydrochloride
Brand: ChemScene
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CAS No. 1221722-25-3
Cat. No. CS-0179644
Purity≥97%
MDL No.MFCD15209627

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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2-Amino-N-(prop-2-yn-1-yl)acetamide hydrochloride|CS-0179644

Structure of 1221722-25-3

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General Information

CAS No. 1221722-25-3
Cat. No. CS-0179644
Purity ≥97%
MDL No. MFCD15209627
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₉ClN₂O
Molecular Weight 148.59
Synonym(s) 2-aMino-N-(prop-2-ynyl)acetaMide hydrochloride
SMILES O=C(NCC#C)CN.[H]Cl

Description

2-Amino-N-(prop-2-yn-1-yl)acetamide hydrochloride features a reactive alkyne handle and a primary amine group, enabling efficient bioconjugation and click chemistry applications. This bench-stable derivative delivers reliable performance in peptide labeling, probe synthesis, and targeted delivery systems under standard conditions.

Application

2-Amino-N-(prop-2-yn-1-yl)acetamide hydrochloride serves as a versatile building block for bioactive molecule synthesis, enabling efficient access to amide-linked scaffolds via standard coupling protocols. The terminal alkyne functionality facilitates CuAAC click chemistry, while the amino and acetamide groups offer orthogonal reactivity for further derivatization. Bench-stable and readily purified by recrystallization, it functions reliably in peptide and heterocyclic synthesis workflows.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Computational Chemistry Data

TPSA 55.12
LogP -0.8837
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 2

Other Classifications

Building Blocks Skeleton Fatty chain compounds

Building Blocks Functional Group Amine

Building Blocks Functional Group Alkyne

Building Blocks Functional Group Amide

Chemical Biology Conjugation Chemistry/Click Chemistry Terminal Alkynes

Chemical Biology Pharmaceutical Development and Drug Discovery Research Conjugation Chemistry/Click Chemistry Terminal Alkynes

Key Words

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2-Amino-N-(prop-2-yn-1-yl)acetamide hydrochloride

CAS No. 1221722-25-3

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