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CS-W001157 4
Total: USD 88.00

2-(2-(tert-Butyl)phenoxy)pyridin-3-amine

  • CAS No. 861673-68-9

  • Cat. No. CS-0154890
  • Molecule weight242.32
  • Purity≥97%
  • MDL No.MFCD11156638

*For research and further manufacturing use only, not for direct human use.

2-(2-(tert-Butyl)phenoxy)pyridin-3-amine|CS-0154890

Structure of 861673-68-9

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General Information

  • CAS No. 861673-68-9
  • Cat. No. CS-0154890
  • Purity ≥97%
  • MDL No. MFCD11156638
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₈N₂O
  • Molecular Weight 242.32
  • Synonym(s) 2-(2-Tert-butylphenoxy)pyridin-3-amine
  • SMILES CC(C)(C)C1=CC=CC=C1OC2=C(C=CC=N2)N

Synthesis

  • Route1
    • 2-(2-(Tert-butyl)phenoxy)-3-nitropyridine|CS-0902415
      861673-67-8
    • ~98%
    • 2-(2-(tert-Butyl)phenoxy)pyridin-3-amine|CS-0154890
      861673-68-9

    References

    • Bristol-Myers Squibb Company Patent: US2006/293522 A1, 2006 ; Location in patent: Page/Page column 19 ; US 20060293522 A1
  • Route2
    • null|null
      88-18-6
    • ~%
    • 2-(2-(tert-Butyl)phenoxy)pyridin-3-amine|CS-0154890
      861673-68-9

    References

    • Chao, Hannguang; Turdi, Huji; Herpin, Timothy F.; Roberge, Jacques Y.; Liu, Yalei; Schnur, Dora M.; Poss, Michael A.; Rehfuss, Robert; Hua, Ji; Wu, Qimin; Price, Laura A.; Abell, Lynn M.; Schumacher, William A.; Bostwick, Jeffrey S.; Steinbacher, Thomas E.; Stewart, Anne B.; Ogletree, Martin L.; Huang, Christine S.; Chang, Ming; Cacace, Angela M.; Arcuri, Maredith J.; Celani, Deborah; Wexler, Ruth R.; Lawrence, R. Michael Journal of Medicinal Chemistry, 2013 , vol. 56, # 4 p. 1704 - 1714
  • Route3

    References

    • Wang, Tammy C.; Qiao, Jennifer X.; Clark, Charles G.; Jua, Ji; Price, Laura A.; Wu, Qimin; Chang, Ming; Zheng, Joanna; Huang, Christine S.; Everlof, Gerry; Schumacher, William A.; Wong, Pancras C.; Seiffert, Dietmar A.; Stewart, Anne B.; Bostwick, Jeffrey S.; Crain, Earl J.; Watson, Carol A.; Rehfuss, Robert; Wexler, Ruth R.; Lam, Patrick Y.S. Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 11 p. 3239 - 3243

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   48.14
  • LogP   3.7536
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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