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Structure of 4783-86-2
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4-Phenoxypyridine serves as a pivotal heterocyclic scaffold in medicinal chemistry, combining a pyridine core with a phenoxyl substituent to deliver enhanced solubility and metabolic stability. This structural motif integrates readily into bioactive molecules, particularly those targeting kinase pathways and CNS receptors. The para-positioned ether linkage enables strategic electronic tuning, while the aromatic system supports π–π stacking interactions in protein binding sites. Its bench-stable nature facilitates handling under standard laboratory conditions.
4-Phenoxypyridine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling reactions. Its pyridine core offers enhanced solubility and metabolic stability, while the phenoxyl group provides a handle for further functionalization. The compound exhibits excellent bench stability and facilitates efficient purification, making it well-suited for high-throughput synthesis and scale-up applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: